Moderna Vaccine Pandemic Pfizer

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## COVID-19 Vaccine by Moderna ### Recent Updates to the Moderna Vaccine Moderna, alongside Pfizer, is one of the mRNA vaccine pioneers for COVID-19. Moderna received full FDA approval in January 2022 after reporting a 94.1% efficacy rate in preventing symptomatic COVID-19 during Phase 3 trials. Moderna's vaccine, mRNA-1273, is a two-dose regimen, with doses given 28 days apart. The vaccine is administered intramuscularly in the upper arm. In June 2022, Moderna announced positive results from a Phase 2/3 study of its Omicron-specific bivalent vaccine. The vaccine, mRNA-1273.214, generated a significantly higher neutralizing antibody response against the Omicron variant compared to the original mRNA-1273 vaccine. ### The Science Behind Moderna's Vaccine Moderna's mRNA vaccine uses messenger RNA (mRNA) to instruct cells to produce the spike protein of the SARS-CoV-2 virus. This spike protein is what the virus uses to attach to and infect human cells. When a person is vaccinated with the Moderna vaccine, the mRNA enters their cells and temporarily reprograms them to produce the spike protein. The immune system then recognizes the spike protein as foreign and mounts an immune response against it. This response includes the production of antibodies that can neutralize the SARS-CoV-2 virus. ### Effectiveness and Safety of the Moderna Vaccine Clinical trials have shown that the Moderna vaccine is highly effective at preventing symptomatic COVID-19. In a Phase 3 trial involving over 30,000 people, the Moderna vaccine was found to be 94.1% effective at preventing symptomatic COVID-19. The Moderna vaccine has also been shown to be safe. The most common side effects are mild to moderate and include: * Pain at the injection site * Fatigue * Headache * Muscle aches * Chills * Fever ### Who Should Get the Moderna Vaccine? The Moderna vaccine is authorized for use in adults and children aged 6 months and older. ### Moderna's Role in the Fight Against the Pandemic Moderna's vaccine has played a critical role in reducing the severity and spread of COVID-19. The vaccine has been distributed to over 100 countries worldwide and has helped protect millions of people from getting sick, being hospitalized, or dying from COVID-19. Moderna is continuing to develop new vaccines and treatments for COVID-19, and its work is vital to the global fight against the pandemic.